Combining Dermal Fillers and Neurotoxins
Dermal fillers and neurotoxins address different contributors to facial lines and volume loss. A combination plan may use fillers such as Restylane®, JUVÉDERM®, or RHA® alongside BOTOX® Cosmetic, Dysport®, Xeomin®, or Daxxify®. These products can be administered during the same visit when that approach fits the treatment plan.
Fillers can add volume to selected areas, while neurotoxins reduce movement in muscles that create dynamic lines. Used strategically, the combination can address fine lines, deeper wrinkles, and sunken cheeks while retaining a natural-looking result. The products, sites, and amount of treatment depend on the areas being addressed.
Concerns a Combination Plan May Address
- Nasolabial folds running from the nose to the corners of the mouth
- Glabellar lines between the eyebrows
- Marionette lines below the corners of the mouth
- Crow’s feet
- Dark circles and under-eye bags
- Forehead lines
- Sunken cheeks
- Thin lips
Some products, including RHA filler and Daxxify, may also be selected when skin quality is part of the concern. A consultation considers which findings are related to volume, muscle movement, or both before recommending a treatment sequence.
What to Expect During Treatment
The injector cleanses the treatment areas and may mark them for accuracy. A topical anesthetic may be used to improve comfort. Injections are brief and may feel like a pinprick. Some dermal fillers are pre-formulated with lidocaine. Afterward, a cold compress may be provided to help minimize swelling.
Filler results are typically visible immediately. Neurotoxin results may begin after several days and can take up to 14 days to reach their full effect. Depending on the products and areas treated, results may last from about 3 months to more than a year. The selected plan provides the best guide to expected timing and duration.
Microdosing Neurotoxins
Microdosing places neurotoxin intradermally rather than into a facial muscle. In this technique, the treatment affects oil glands and can decrease oil production. It may be considered for acne, rosacea, or an appearance sometimes described as a glass facial. Whether microdosing belongs in a broader injectable plan depends on the concern and treatment area.

